Biotechnology
Acologix, Inc. 
Hayward, California USA
Improves patients' lives by developing and commercializing innovative biopharmaceuticals targeting "osteo-renal" (bone and kidney) diseases
A-CUBE, Inc.
Burlingame, California USA
Accurately predict antigen sites and generate antibodies with special functionalities using high performance computer platforms and 3D structural information of target, disease-causing proteins to reduce the time and cost of developing antibody medicine candidates
Acucela, Inc.
Bothell, Washington USA
Provider of new drug therapies for eye diseases, neurodegenerative retinal diseases such as macular degeneration, Stargardt's disease, retinitis pigmentosa and glaucoma
Chiome Bioscience, Inc.
Bunkyo, Tokyo Japan
Provides contract screening of monoclonal antibodies by using its proprietary ADLib® system for both industrial and academic institutions.The ADLib® (autonomous diversifying library) system is a cutting-edge technology that enables the generation of monoclonal antibodies within a few weeks with a minimal amount of antigens
Immunas Pharma, Inc.
(Subsidiary of OncoTherapy Science, Inc.)
Kawasaki, Kanagawa Japan
Specializes in antibody drugs research and development for Cancer and Alzheimer's disease, by being specific to and neutralizing soluble Aβ oligomers, the true cause of the neurotoxicity in patients with Alzheimer's
ImmunoFrontier, Inc.
Chuou, Tokyo Japan
Drug discovery company focused on the development of cutting-edge therapeutic vaccines for cancers and immunotherapeutics
Medical Collective Intelligence Co., Ltd. (MCI)
Chuou, Tokyo Japan
Provider of marketing support services for pharmaceutical and healthcare companies. MCI was established in May 2007 as a spin-off company from a management consulting company, Link Consulting Associates Japan Corporation
Medical Devices
Avantis Medical Systems, Inc.
Sunnyvale, California USA
Developer and manufacturer of catheter-based endoscopic devices. Its initial focus is on devices for use in both detecting and treating cancers of the gastrointestinal (GI) tract.
Bioabsorbable Therapeutics, Inc.
Menlo Park, California USA
Developer of next generation of medical devices for treating vascular disease. In particular, the company aims to utilize novel, proprietary anti-inflammatory polymers to create fully bioabsorbable stents and related products
Broncus Technologies, Inc.
Mountain View, California USA
Developer of the Exhale® Emphysema Treatment System, a new interventional bronchoscopic technology to treat patients with emphysema. This system presently is undergoing clinical evaluation.
Chestnut Medical Technologies. Inc.
Menlo Park, California USA
— Acquired by EV3 (NASDAQ: EVVV)
Develops medical devices to fulfill unmet needs in Interventional Neuroradiology
Ellipse Technologies, Inc.
Irvine, California USA
Development stage medical device company that develops “Dynamic Remodeling Systems” for multiple application through the body. Initial indications include abnormal curvature of the spine and morbid obesity
Insound Medical, Inc.
Newark, California USA
Developer of the World’s first extended wear device worn continuously in the ear canal for 4-6 months, even during sleep, shower and swimming
Interventional Spine, Inc.
Irvine, California USA
Exclusively focused on the design, development and marketing of patented PERCUTANEOUS systems to treat lower back pain
MiCardia Corporation
Irvine, California USA
Utilizes superior medical advancements to develop minimally invasive technology. It is currently focusing on methods that allow cardiologists working in a catheter lab environment to treat Mitral Valve Regurgitation and Congestive Heart Failure Caused by Ventricular Dilation
Micrus Endovascular Corporation
San Jose, California USA
— Nasdaq; MEND
Manufacturer of both implantable and disposable medical devices used in the treatment of cerebral vascular diseases.
Reverse Medical Corporation
Irvine, California USA
Development stage medical device company that initially focuses on developing catheter based embolic protection devices for neurovascular application
Spineworks Medical, Inc.
San Jose, California USA
Early stage medical device company developing minimally-invasive orthopedic product line. Its initial focus is to repair vertebrae compression fracture.